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DT-Web is a web-based application for drug-target interaction and drug combination prediction through domain-tuned network-based inference. The interface to the DT-Hybrid algorithm, applies a recommendation technique based on bipartite network projection implementing resources transfer within the network. This technique combined with domain-specific knowledge expressing drugs and targets similarity is used to compute recommendations for each drug.
Our web interface offers the following features:
Our system is periodically synchronized with DrugBank and PathwayCommons. Predictions are updated accordingly.
The website is free and open to all users.
You can find full article at: Pubmed, BMC, ResearchGate and so on.